| Termijn | Thuis | Uitteam | Uitslag |
|---|---|---|---|
| 22-2-25 22:45 | Los Angeles FC | Minnesota United FC | 1:0 |
| 23-2-25 1:30 | Orlando City | Philadelphia Union | 2:4 |
| 23-2-25 1:30 | D.C. United | Toronto FC | 2:2 |
| 23-2-25 1:30 | Columbus Crew | Chicago Fire | 4:2 |
| 23-2-25 1:30 | FC Cincinnati | New York Red Bulls | 1:0 |
| 23-2-25 1:30 | Atlanta United FC | CF Montreal | 3:2 |
| 23-2-25 1:30 | Inter Miami CF | New York City FC | 2:2 |
| 23-2-25 2:30 | St. Louis City SC | Colorado Rapids | 0:0 |
| 23-2-25 2:30 | Nashville SC | New England Revolution | 0:0 |
| 23-2-25 2:30 | Houston Dynamo | FC Dallas | 1:2 |
| 23-2-25 2:30 | Austin FC | Sporting Kansas City | 1:0 |
| 23-2-25 4:30 | Seattle Sounders | Charlotte FC | 2:2 |
| 23-2-25 4:30 | San Jose Earthquakes | Real Salt Lake | 4:0 |
| 23-2-25 22:00 | Portland Timbers | Vancouver Whitecaps | 1:4 |
| 24-2-25 1:00 | Los Angeles Galaxy | San Diego FC | 0:2 |