| Termijn | Thuis | Uitteam | Uitslag |
|---|---|---|---|
| 29-3-25 19:30 | New England Revolution | New York Red Bulls | -:- |
| 29-3-25 19:30 | Toronto FC | Vancouver Whitecaps | -:- |
| 29-3-25 21:30 | Colorado Rapids | Charlotte FC | -:- |
| 30-3-25 0:30 | Atlanta United FC | New York City FC | -:- |
| 30-3-25 0:30 | D.C. United | Columbus Crew | -:- |
| 30-3-25 0:30 | Inter Miami CF | Philadelphia Union | -:- |
| 30-3-25 1:30 | FC Dallas | Sporting Kansas City | -:- |
| 30-3-25 1:30 | Chicago Fire | CF Montreal | -:- |
| 30-3-25 1:30 | Minnesota United FC | Real Salt Lake | -:- |
| 30-3-25 1:30 | Nashville SC | FC Cincinnati | -:- |
| 30-3-25 4:30 | San Jose Earthquakes | Seattle Sounders | -:- |
| 30-3-25 4:30 | Los Angeles Galaxy | Orlando City | -:- |
| 30-3-25 4:30 | San Diego FC | Los Angeles FC | -:- |
| 30-3-25 20:15 | St. Louis City SC | Austin FC | -:- |
| 31-3-25 1:00 | Portland Timbers | Houston Dynamo | -:- |